Association between CYP2C19 genotype and proguanil oxidative polymorphism
نویسندگان
چکیده
منابع مشابه
Association between CYP2C19 genotype and proguanil oxidative polymorphism.
AIMS To examine the relationship between proguanil metabolism and the number of mutations in CYP2C19 by comparing the CYP2C19 genotype and proguanil phenotype of 10 subjects. METHODS Partial clearance and urinary metabolic ratio data were obtained from a previous study of 10 subjects [5]. Analysis of CYP2C19 genotypes was performed using PCR amplification followed by restriction endonuclease ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1997
ISSN: 0306-5251
DOI: 10.1046/j.1365-2125.1997.00596.x