Association of MBL2 Exon 1 Polymorphisms With Multibacillary Leprosy
نویسندگان
چکیده
منابع مشابه
Efficacy of different regimens in multibacillary leprosy.
The necessity for combined chemotherapy in multi bacillary leprosy has been recognized for about 1 5 years . I-3 It was however entirely unknown how this combined therapy had to be applied, particularly in respect to the drugs to be given, the frequency of their administration and above all the duration of therapy. We have approached the problem on the basis of results obtained in experimental ...
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380 multibacillary leprosy patients were treated with combined chemotherapy at Anandaban leprosy hospital in Nepal. The drugs used were Rifampicin, Dapsone, Clofazamine and Iso-prodian. This treatment is modelled on the short course chemotherapy of tuberculosis. A remarkable clinical and bacteriological improvement was observed in all patients. Group A patients were bacteriologically negative a...
متن کاملAn Unsuspected Case of Relapsed Multibacillary Leprosy
Received January 22, 2013, Revised February 15, 2013, Accepted for publication February 27, 2013 Corresponding author: Hyun Sun Park, Department of Dermatology, Seoul National University Boramae Hospital, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 156-707, Korea. Tel: 82-2-870-3669, Fax: 82-2870-2866, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creativ...
متن کاملAssociation of Single-Nucleotide Polymorphisms of the MBL2 with Atopic Dermatitis in Korean Patients
BACKGROUND Human mannose-binding lectin (MBL) is a serum lectin taking part in the innate immunity by opsonizing various microorganisms for phagocytosis. The MBL serum concentration is affected by several single-nucleotide polymorphisms (SNPs) in the promoter region of the MBL2 gene. OBJECTIVE The purpose of this study was to examine the relationship between MBL2 polymorphisms and atopic derm...
متن کاملIncreased hepcidin expression in multibacillary leprosy.
Iron is essential for all organisms and its availability can control the growth of microorganisms; therefore, we examined the role of iron metabolism in multibacillary (MB) leprosy, focusing on the involvement of hepcidin. Erythrograms, iron metabolism parameters, pro-inflammatory cytokines and urinary hepcidin levels were evaluated in patients with MB and matched control subjects. Hepcidin exp...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2020
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.01927