Asymmetric Aldol/Vinylogous Aldol/Cyclization Reaction Using Phosphine Oxide Catalysts
نویسندگان
چکیده
منابع مشابه
Asymmetric α-amination of 3-substituted oxindoles using chiral bifunctional phosphine catalysts
A highly enantioselective α-amination of 3-substituted oxindoles with azodicarboxylates catalyzed by amino acids-derived chiral phosphine catalysts is reported. The corresponding products containing a tetrasubstituted carbon center attached to a nitrogen atom at the C-3 position of the oxindole were obtained in high yields and with up to 98% ee.
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ژورنال
عنوان ژورنال: CHEMICAL & PHARMACEUTICAL BULLETIN
سال: 2017
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c17-00540