Atrial Fibrillation and the Hypercoagulable State: From Basic Science to Clinical Practice
نویسندگان
چکیده
منابع مشابه
Atrial fibrillation and the hypercoagulable state: from basic science to clinical practice.
Atrial fibrillation (AF) is the commonest sustained cardiac rhythm disturbance in clinical practice [1]. Its presence increases mortality by two-fold [2], mostly by increasing the risk of stroke and thromboembolism. The reasons for stroke occurring in AF are multiple and complex, but many strokes related to AF represent embolism of thrombus formed within the left atrium (LA), predominantly with...
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Heart failure (HF) and atrial fibrillation (AF) are two growing epidemics associated with significant morbidity and mortality. They often coexist due to common risk factors and shared pathophysiological mechanisms. Patients presenting with both HF and AF have a worse prognosis and present a particular therapeutic challenge to clinicians. This review aims to appraise the common pathophysiologica...
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Sudden cardiac death refers to unexpected death attributable to a cardiac cause occurring within 1 h of the onset of symptoms (NICE, 2006). It often results from cardiac arrhythmias and is a major worldwide cause of morbidity and mortality. Arrhythmias account for 180,000 to 250,000 deaths per year in the United States and ∼70,000 deaths per year in the United Kingdom (NICE, 2006; Chugh et al.,...
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BACKGROUND AND PURPOSE Secondary prevention trials do not distinguish outcomes according to stroke cause. The purpose of the study was to determine whether trial efficacy of anticoagulation for secondary prevention could be replicated in clinical practice in strokes of different etiology. METHODS A 2-year observation study was undertaken in 288 stroke patients with atrial fibrillation (mean a...
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ژورنال
عنوان ژورنال: Pathophysiology of Haemostasis and Thrombosis
سال: 2003
ISSN: 1424-8832,1424-8840
DOI: 10.1159/000083815