Autism spectrum disorders—A genetics review
نویسندگان
چکیده
منابع مشابه
Autism spectrum disorder in the genetics clinic: a review.
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders affecting social communication, language and behavior. The underlying cause(s) in a given individual is often elusive, with the exception of clinically recognizable genetic syndromes with readily available molecular diagnosis, such as fragile X syndrome. Clinical geneticists approach patients with ASDs by...
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We review the current status of the role and function of the mitochondrial DNA (mtDNA) in the etiology of autism spectrum disorders (ASD) and the interaction of nuclear and mitochondrial genes. High lactate levels reported in about one in five children with ASD may indicate involvement of the mitochondria in energy metabolism and brain development. Mitochondrial disturbances include depletion, ...
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Autism is a neurodevelopmental disorder of complex etiology and is amongst the most heritable of neuropsychiatric disorders while sharing genetic liability with other neurodevelopmental disorders such as intellectual disability (ID). Autism spectrum disorders (ASDs) are defined more broadly and include autism, Asperger syndrome, childhood disintegrative disorder and pervasive developmental diso...
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Objectives: The involvement of parents in raising children with autism spectrum disorder (ASD) is crucial for both the child's development and family functioning. However, studies relating to parental involvement in parenting children with ASD mainly focus on the mother's perspective, resulting in a lack of understanding of the father's role. On the other hand, the father involvement in parenti...
متن کاملREVIEW ARTICLE The Genetics of Autism
Autism is a complex, behaviorally defined, static disorder of the immature brain that is of great concern to the practicing pediatrician because of an astonishing 556% reported increase in pediatric prevalence between 1991 and 1997, to a prevalence higher than that of spina bifida, cancer, or Down syndrome. This jump is probably attributable to heightened awareness and changing diagnostic crite...
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ژورنال
عنوان ژورنال: Genetics in Medicine
سال: 2011
ISSN: 1098-3600,1530-0366
DOI: 10.1097/gim.0b013e3181ff67ba