Avidity of CD8 T cells sharpens immunodominance
نویسندگان
چکیده
منابع مشابه
Avidity of CD8 T cells sharpens immunodominance.
In the course of viral infection, the immune system exploits only a fraction of the available CTL repertoire and focuses on a few of a myriad of potentially antigenic peptides. This phenomenon, known as immunodominance, depends on a number of factors, including antigen processing and transport, MHC binding, competition for antigen-presenting cells, availability of the CD8 T cell repertoire and ...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2007
ISSN: 0953-8178,1460-2377
DOI: 10.1093/intimm/dxm016