Axillary metastasis in clinically node-negative breast cancer

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Breast Axillary Lymph Node Metastasis

1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, 3800 Reservoir Road NW, Washington, DC 20007, USA 2Clinical Breast Care Project, 620 Seventh Street, Windber, PA 15963, USA 3Division of Oncogenomics, Department of Pathology, University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany 4Department of Pathology, University of Milan School o...

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Factors influencing axillary lymph node metastasis in invasive breast cancer.

PURPOSE To explore the relationship between auxiliary lymph node metastasis and clinical features, and to identify the factors that affect metastasis occurrence. METHODS A total of 164 cases of primary breast cancer were selected to investigate features such as age, concomitant chronic disease and pathologic diagnosis. Immunohistochemistry was used to detect the expression of the estrogen rec...

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Axillary recurrence in sentinel lymph node-negative breast cancer patients.

BACKGROUND Sentinel lymph node biopsy (SLNB) was developed to axillary lymph node dissection (ALND) in the treatment of breast cancer. SLNB is predictive of axillary node status. Major concern is the occurrence of a false-negative SLN. Purpose of this study is to determine the rate of axillary recurrence in our series of unselected patients. PATIENTS AND METHODS All patients with a negative S...

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Prognostic factors in axillary node-negative breast cancer.

In node-negative breast cancer, advices for adjuvant therapy are based on traditional factors like age, tumour size, grade of differentiation, and steroid hormone receptor status. Several new factors that may better describe tumour behaviour, like proliferation rate (determined by thymidine labelling index, S-phase fraction, mitotic index, or Ki-67), presence of disseminated tumour cells, as we...

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Feasibility of sentinel lymph node biopsy in breast cancer patients clinically suspected of axillary lymph node metastasis on preoperative imaging

BACKGROUND Generally, sentinel lymph node biopsy (SLNB) is performed in patients with clinically negative axillary lymph node (LN). This study was to assess imaging techniques in axillary LN staging and to evaluate the feasibility of SLNB in patients clinically suspected of axillary LN metastasis on preoperative imaging techniques (SI). METHODS A prospectively maintained database of 767 breas...

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ژورنال

عنوان ژورنال: Journal of the Egyptian National Cancer Institute

سال: 2018

ISSN: 1110-0362

DOI: 10.1016/j.jnci.2018.09.001