Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

Serotonin. Current aspects of neurochemistry and function.

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Molecular and Cellular Aspects of Rhabdovirus Entry

Rhabdoviruses enter the cell via the endocytic pathway and subsequently fuse with a cellular membrane within the acidic environment of the endosome. Both receptor recognition and membrane fusion are mediated by a single transmembrane viral glycoprotein (G). Fusion is triggered via a low-pH induced structural rearrangement. G is an atypical fusion protein as there is a pH-dependent equilibrium b...

Polypeptide Hormones : molecular and cellular aspects

Synaptic plasticity-molecular, cellular, and functional aspects.

The ability of synapses to change their properties, either by gain or loss of entire synapses or by alteration of efficiency of signal transduction within individual synapses, is an essential feature of complex nervous systems that alter their response over time. While learning and memory represent perhaps the most obvious application of this "plasticity", the changes seen during development an...

Cellular and molecular aspects of inflammation.

Cellular host reaction to noxious agents and damaging events consists of inflammatory, immune and repair responses. These are usually involved in different phases of the host reaction in a well co-ordinated manner, contributing to the well-being of the host. However, when they are excessive, uncontrolled or occur in a vulnerable anatomic location, they can contribute greatly to injury. In gener...