Basic Principles of Interpretation of Hepatocellular Hypertrophy in Risk Assessment in Japan
نویسندگان
چکیده
منابع مشابه
[Basic principles of interpretation of hepatocellular hypertrophy in risk assessment in Japan].
This article provided a scientific basis for determining whether liver hypertrophy, a common change in the liver induced by xenobiotics in toxicological studies, is an adaptive or adverse event. To maintain homeostasis in the whole organism, the liver frequently responds to xenobiotic exposure by increasing metabolic capacity via nuclear receptor activation. The resuiting hepatic adaptive respo...
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ژورنال
عنوان ژورنال: Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
سال: 2015
ISSN: 0015-6426,1882-1006
DOI: 10.3358/shokueishi.56.42