Bcl-2 proteins: Unraveling the details of a complex and dynamic network
نویسندگان
چکیده
منابع مشابه
the investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
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15 صفحه اولRegulation of mammalian target of rapamycin complex 1 by Bcl-2 and Bcl-XL proteins.
Mammalian target of rapamycin complex 1 (mTORC1) is a key regulator of cell growth and metabolism. Its activity is controlled by various types of signals, including growth factors, nutrients, and stresses. In this study, we show that changes in expression levels of two antiapoptotic proteins, Bcl-2 and Bcl-XL, also affect mTORC1 signaling activity. In cells overexpressing Bcl-XL, mTORC1 activit...
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NADPH OXIDASE (NOX)-mediated generation of reactive oxygen species (ROS) was first described in phagocytic cells, and for many years it was assumed that the primary role of NADPH oxidase activation was bacteriocidal; phagocytes generated a burst of ROS following activation. More recently, it has become clear that not only do multiple homologous NADPH oxidase subunits exist but that the expressi...
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ژورنال
عنوان ژورنال: Molecular & Cellular Oncology
سال: 2017
ISSN: 2372-3556
DOI: 10.1080/23723556.2017.1384880