Beating cancer in multiple ways using nanogold

Multiple crashes on motor ways.

Biopharmaceutical applications of nanogold.

The application of nanogold in biopharmaceutical field is reviewed in this work. The properties of nanogold including nanogold surface Plasmon absorption and nanogold surface Plasmon light scattering are illustrated. The physical, chemical, biosynthesis methods of nanogold preparation are presented. Catalytic properties as well as biomedical applications are highlighted as one of the most impor...

PML Degradation: Multiple Ways to Eliminate PML

The promyelocytic leukemia tumor suppressor gene (PML) critically regulates several cellular functions that oppose tumorigenesis such as oncogene-induced senescence, apoptosis, the response to DNA damage and to viral infections. PML deficiency occurs commonly in a broad spectrum of human cancers through mechanisms that involve its aberrant ubiquitination and degradation. Furthermore, several vi...

Ways of dying: multiple pathways to apoptosis.

In order to eliminate cells that are redundant, damaged, or infected, metazoan organisms have evolved the cell suicide mechanism termed apoptosis (Kerr et al. 1972). This genetic program is vital for normal development, for maintenance of tissue homeostasis, and for an effective immune system. Not surprisingly therefore, its disturbance is implicated in numerous pathological conditions, ranging...

Cancer spies find drug-beating covert cells

By spying on cancer cells, Novartis researchers have a made a preliminary discovery that could potentially shape how targeted therapies are combined to treat patients. Currently doctors use the genomic profile of a patient’s tumor to select drugs that will hit the right target and shrink the cancer. Targeted therapy has prolonged many lives, but most cancers come back, and these drug-resistant ...