Behavioral mechanisms of context fear generalization in mice
نویسندگان
چکیده
منابع مشابه
Neurobehavioral mechanisms of human fear generalization
While much research has elucidated the neurobiology of fear learning, the neural systems supporting the generalization of learned fear are unknown. Using functional magnetic resonance imaging (fMRI), we show that regions involved in the acquisition of fear support the generalization of fear to stimuli that are similar to a learned threat, but vary in fear intensity value. Behaviorally, subjects...
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In Pavlovian fear conditioning, a conditional stimulus (CS, usually a tone) is paired with an aversive unconditional stimulus (US, usually a foot shock) in a novel context. After even a single pairing, the animal comes to exhibit a long-lasting fear to the CS and the conditioning context, which can be measured as freezing, an adaptive defense reaction in mice. Both context and tone conditioning...
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ژورنال
عنوان ژورنال: Learning & Memory
سال: 2016
ISSN: 1549-5485
DOI: 10.1101/lm.042374.116