Beta-blockade--rational or irrational therapy for congestive heart failure?

EDITORIAL / - Blockade - rational or irrational therapy for congestive heart failure ?

CLINICAL AND BASIC RESEARCH in the arena of congestive heart failure is intensive. Nevertheless, accepted treatment modalities for patients with this debilitating and fatal disease are limited to just three: digitalis, diuretics, and vasodilators, and only the latter has been demonstrated to improve survival in patients with congestive heart failure.1 Although cardiac transplantation markedly r...

EDITORIAL / - Blockade - rational or irrational therapy for congestive heart failure ? JEFFREY

CLINICAL AND BASIC RESEARCH in the arena of congestive heart failure is intensive. Nevertheless, accepted treatment modalities for patients with this debilitating and fatal disease are limited to just three: digitalis, diuretics, and vasodilators, and only the latter has been demonstrated to improve survival in patients with congestive heart failure.1 Although cardiac transplantation markedly r...

antibiotic prescribing review: rational or irrational therapy?

Beta-blockers for congestive heart failure.

The prognosis of patients with congestive heart failure (CHF) can be significantly improved with drug therapy targeted at the renin-angiotensin and adrenergic nervous system. beta-adrenergic blocking drugs, once contraindicated in CHF, have now been shown to improve survival in CHF.

Endothelin receptor blockade in congestive heart failure.

Heart Failure To the Editor: Of the many new therapeutic agents for slowing the progression of congestive heart failure (CHF), other than antagonizing the renin-angiotensin-aldosterone system, blocking the endothelin receptors seems to be most promising. The two latest reports published in Circulation1,2 render further support to this exciting concept. Endothelin may contribute to the symptoms ...