Biodistribution of HuCC49ΔCH2-β-galactosidase in colorectal cancer xenograft model
نویسندگان
چکیده
منابع مشابه
Intracaecal Orthotopic Colorectal Cancer Xenograft Mouse Model.
The host microenvironment plays a prominent role in tumor growth, angiogenesis, invasion, metastasis, and response to therapy. Orthotopic tumor model mimics the natural environment of tumor development and provides an effective approach to investigate tumor pathophysiology and develop therapeutic strategies. This protocol describes the technique involving injection of colorectal cancer cell sus...
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es, such as α-mannosidases (MAN) and β-galactosidases (GAL), are found in different glycoside hydrolase sequencebased families. Considerable research has proved plays the role of MAN, which play a key role in the modification and diversification of hybrid N-glycans, processes with strong cellular links to cancer. Therefore the study aim was to investigate the activities of MAN and GAL in larynx...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2010
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2009.11.020