Biological functions of complement
نویسندگان
چکیده
منابع مشابه
Biological functions of the complement system.
T h e phenomenology of the complement system was quite extensively worked out by the early IY4Os when the four classical complement components. C'l, C'4. C'3 and C'2, had been described as had the 'anlage' of the observations that there were multiple pathways of activation. In the lY6Os, the complement components were purified as proteins and as antigens. T h e biochemistry of their interaction...
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Complement is a system of serum proteins whose main function is to defend the body against infection. Although it has a reputation as a dauntingly complex system, this results chiefly from confusion in the nomenclature, which has varied considerably with time as more components were discovered, for example as ‘component C3’ became subdivided into several components one of which is still called ...
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The importance of C5 in the generation of complement (C)-dependent chemotactic activity in vitro is well recognized. However, the actual role C5 may play in the accumulation of polymorphonuclear leukocytes (PMN) at inflammatory sites in vivo has not been established. Injection of glycogen or endotoxin into the peritoneal cavities of guinea pigs resulted, shortly thereafter, in the local accumul...
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ژورنال
عنوان ژورنال: Bulletin of Siberian Medicine
سال: 2007
ISSN: 1819-3684,1682-0363
DOI: 10.20538/1682-0363-2007-2-72-82