Biological membranes: aberrations in membrane structure and function

Biological membrane structure, I. The protein crystal model for membranes.

A geometric model for the arrangement of phospholipid and protein in biological membrane systems has been proposed. The essential principle underlying this model is that when membrane proteins polymerize, the points of contact between proteins are few, and cavities lined with predominantly nonpolar amino acids are formed. Phospholipid molecules become oriented with the fatty chains inserted int...

Biological Membranes Architecture and Function

Structure and Function of Membranes

As stated in the introduction by R. A. Peters, the purpose of this issue of the British Medical Bulletin "is to present a cross section of the research now in progress in this field of membranes." Although the coverage of the field is by no means complete, this purpose is achieved reasonably well in a series of short and concise reviews by investigators who are actively working on the problems ...

Permeability and Function of Biological Membranes

with the history of cardiac surgery, there may be difficulty in finding the reference to a particular point. Usually, however, the major points are indexed and it is only ones ancillary to cardiac surgery that one must search for. The margins are liberally sprinkled with line drawings of many of the pioneers. The sketches add charm to the presentation, even though they are not always good liken...

Membrane Structure and Function

An understanding of the biochemical basis of membrane function is an important goal of present day biology. In this paper, a biochemical approach to the problem of the specific transport of sugars across the membrane of Escherichia coli is discussed. A new biochemical model for lactose transport system in this organism is presented, in which a specific membrane protein (M protein) plays the rol...