Biosimilars are becoming indispensable in the management of multiple diseases although concerns still exist

Are Biosimilars Identical to the Reference Products?

Management of Candiduria: Grey Zones Still Exist

Critically ill patients are a susceptible group for opportunistic Candida infections. The major risk factors identified with candiduria are extremes of age, female sex, diabetes mellitus, use of immunosuppressive agents, interruption of the flow of urine, radiation therapy, and so on. However, in nosocomial settings, the major risk factors are the use of urinary catheters and the prior use of b...

Are Biosimilars Identical to the Reference Products?

In U.S., biosimilars still await FDA decision.

Offi cials at the U.S. Food and Drug Administration have yet to announce if and when they plan to begin accepting abbreviated applications for follow-on biologics (referred to as " biosimilar " drugs in Europe), but experts said they do not expect anything from the agency soon. Generic biologic agents can still be approved through a new-drug application (NDA), but the burden of proof that comes...

What are the origin and route of diseases in Iran?

Since the gens change due to the environmental and individual factors, the role of these factors is now more important for the human health. In countries that the facilities such as clean air, healthy water and food, sport and recreational sites, social security and disease prevention programs readily available for all, the society is healthy and happy. Thus, the overall morbidities and mortali...