Bipolar disorder and age-related functional impairment

Bipolar disorder and age-related functional impairment Prejuízo funcional associado à idade e transtorno bipolar Correspondence

1 Molecular Psychiatry Laboratory & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre (RS), Brazil 2 Bipolar Disorders Program, Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, Barcelona, Spain Abstract Objective: Although bipolar disorder is a major contributor to functional imp...

Neurocognitive impairment in bipolar disorder patients: functional implications.

BACKGROUND Functional recovery among treated bipolar disorder (BPD) patients is far less likely than syndromal and even symptomatic recovery. We hypothesized that increasingly well-documented aspects of cognitive impairment may contribute to poor functional outcomes in BPD patients, and reviewed the available research on the topic. METHODS Computerized literature searching identified 12 studi...

Functional impairment in patients with remitted bipolar disorder.

Cognitive impairment in bipolar disorder.

AIM Provide an overview of how bipolar disorder affects cognitive function in patients. METHODS MEDLINE and PsycInfo data bases were searched for articles indexed by the combinations of MESH term or key word "bipolar disorder" with the following terms: "cognition", "memory", "neuropsychology", "neuropsychological tests", "lithium", "anticonvulsants", "antipsychotics", and "schizophrenia". Con...

Cognitive impairment and dementia in bipolar disorder.

In bipolar disorder (BD), impaired cognition has long been described as a psychopathological feature of abnormal mood states, or accepted as treatment related side-effects. More recently, neuropsychological studies conducted in older adults have led to the recognition that enduring, irreversible cognitive changes do occur in substantial proportion of euthymic patients with life-long BD, relevan...