BIRC5 is a prognostic biomarker associated with tumor immune cell infiltration

Urinary neutrophil-gelatinase associated lipocalin is a more prognostic biomarker to distinguish antenatal hydronephrosis in neonates

Background: Routine diagnostic methods of Vesicoureteral reflux (VUR) are invasive and can cause exposure to radiation and may increase risk of urinary tract infections. Therefore, introducing reliable, non invasive methods might be more interested in pediatric nephrology. The objective of this perspective case control study was to evaluate the prognostic value of urinary neutrophil-gelatinase ...

urinary neutrophil-gelatinase associated lipocalin is a more prognostic biomarker to distinguish antenatal hydronephrosis in neonates

background: routine diagnostic methods of vesicoureteral reflux (vur) are invasive and can cause exposure to radiation and may increase risk of urinary tract infections. therefore, introducing reliable, non invasive methods might be more interested in pediatric nephrology. the objective of this perspective case control study was to evaluate the prognostic value of urinary neutrophil-gelatinase ...

T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G

Ewing sarcoma (EwS) is an aggressive mesenchymal cancer of bones or soft tissues. The mechanisms by which this cancer interacts with the host immune system to induce tolerance are not well understood. We hypothesized that the non-classical, immune-inhibitory HLA-molecule HLA-G contributes to immune escape of EwS. While HLA-Gpos suppressor T cells were not increased in the peripheral blood of Ew...

PSMB7 is associated with doxorubicin resistance and is a prognostic biomarker in breast cancer

Infiltration of tumor‐associated macrophages is involved in CD44 expression in clear cell renal cell carcinoma

Cancer stem-like cells (CSC) or cancer-initiating cells are now considered to be an important cell population related to cancer recurrence and the resistance to anti-cancer therapy. Tumor-associated macrophages (TAM) are a main component of stromal cells and are related to cancer progression in clear cell renal cell carcinoma (ccRCC). Because the detailed mechanisms allowing the maintenance of ...