Blepharitis: a rare side effect related to cetuximab in patient with colorectal cancer

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[Blepharitis related to Cetuximab treatment in an advanced colorectal cancer patient].

CASE REPORT A 52-year-old woman with advanced colorectal cancer was referred to us for treatment of Cetuximab-related ocular side-effects. DISCUSSION Cetuximab is a monoclonal antibody that specifically blocks epidermal growth factor receptor activity. It has recently been approved to treat some tumors such as metastatic colorectal cancer and some ORL cancers. Tolerance to it seems to be bett...

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Combination effect of cetuximab with radiation in colorectal cancer cells.

AIMS AND BACKGROUND Colorectal cancer (CRC) is one of the commonest malignant disorders and frequently associated with high expression of epidermal growth factor receptor (EGFR), resulting in advanced disease and a poor prognosis. In this study, we investigated the radiosensitizing effects of the selective EGFR inhibitor cetuximab in human CRC cell lines. METHODS Four human CRC cell lines, Ca...

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A Rare Presentation of Arterial Thrombosis after Venous Thrombosis in a Patient with Gastric Cancer

Background: Venous thromboembolism, which comprises deep vein thrombosis and pulmonary embolism and is a significant cause of morbidity and mortality among patients with cancer. The aim of the present study was to report a rare presentation of arterial thrombosis after venous thrombosis in a patient with gastric cancer. Report of the Case: A 45 year-old female patient with locally advanced gas...

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Cetuximab treatment in a patient with metastatic colorectal cancer and psoriasis

Cetuximab, a monoclonal antibody directed against the epidermal growth factor receptor, has activity against colorectal cancer. Treatment is associated with skin toxicity, and the safety of cetuximab in patients with psoriasis is unknown. We report the case of a male patient with stage iv colorectal cancer (crc) and a life-long history of extensive psoriasis. This patient experienced a durable ...

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A rare but severe pulmonary side effect of cetuximab in two patients.

Cetuximab is a monoclonal antibody that treats malignant disease by inhibiting epidermal growth factor receptor. Many common adverse events have been reported and include skin rashes, infusion reactions, gastrointestinal complaints and headache. Up to now, cetuximab-associated pulmonary toxicity has been rarely reported in the literature. The present report describes two cases with probable int...

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ژورنال

عنوان ژورنال: BMJ Case Reports

سال: 2019

ISSN: 1757-790X

DOI: 10.1136/bcr-2019-231774