Blockade of Interleukin-6 Receptor Alleviates Disease in Mouse Model of Scleroderma
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چکیده
منابع مشابه
Interleukin-6 receptor blockade suppresses subretinal fibrosis in a mouse model.
AIM To determine the involvement of the interleukin (IL)-6 with the development of experimental subretinal fibrosis in a mouse model. METHODS Subretinal fibrosis was induced by subretinal injection of macrophage-rich peritoneal exudate cells and the local expression of IL-6 was assessed by quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR) and enzyme-linked immuno...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2012
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2011.09.013