<b>NATURAL DECREASING TEMPERATURE AND PHOTOPERIOD CONDITIONS OR ACUTE COLD EXPOSURE AFFECT CIRCULATING THYROID HORMONES, SERUM CHOLESTEROL AND TYPE II 5'-DEIODINASE IN BROWN ADIPOSE TISSUE IN THE TRUMPET-TAILED RAT,<i> OCTODON </i></b><b><i>DEGUS </i></b>
نویسندگان
چکیده
منابع مشابه
Types I and II iodothyronine 5'-deiodinase activities in perirenal brown adipose tissue of neonatal goats.
The perirenal adipose tissue is the main fat depot in newborn goats, and it has recently been shown to represent functional "brown fat" [l]. In the rat, brown adipose tissue contains a high activity of the iodothyronine 5'deiodinase enzyme system which converts thyroxine to the active thyroid hormone, 3,3',5-triiodothyronine [see 21. Iodothyronine 5'deiodinase exists in two major forms, termed ...
متن کاملPotential of brown adipose tissue type II thyroxine 5'-deiodinase as a local and systemic source of triiodothyronine in rats.
Previous reports suggest that a type II iodothyronine 5'-deiodinase may become the main enzymatic pathway for extrathyroidal triiodothyronine (T3) generation when the enzyme levels are sufficiently elevated and/or liver and kidney type I 5'-deiodinase activity is depressed. The present studies assessed the potential of brown adipose tissue (BAT) type II 5'-deiodinase to generate T3 for the plas...
متن کاملThyrotropin receptors in brown adipose tissue: thyrotropin stimulates type II iodothyronine deiodinase and uncoupling protein-1 in brown adipocytes.
It has been demonstrated that TSH receptors are expressed not only in thyroid gland but also in extrathyroidal tissues. Brown adipose tissue of guinea pig has been reported to express TSH receptor messenger RNA (mRNA), but the physiological roles of TSH receptors in brown adipose tissue have not been understood. We studied the expression and function of TSH receptors in rat brown adipose tissue...
متن کاملlodothyronine 5 ' - deiodinase activity and thyroid hormone content in brown adipose tissue during the breeding cycle of the rat
Brown adipose tissue iodothyronine 5'-deiodinase activity is significantly lower in 17-day pregnant rats compared with virgin controls and remains low during late pregnancy and lactation. It fully recovers with abrupt weaning, but only partially with spontaneous weaning. Even though this profile of changes is remarkably in step with the known pattern of modifications in brown fat thermogenesis ...
متن کاملAcute cold exposure, leptin, and somatostatin analog (octreotide) modulate thyroid 5'-deiodinase activity.
We investigated the effect of acute cold exposure, leptin, and the somatostatin analog octreotide (OCT) on thyroid type I (D1) and II (D2) deiodinase activities. Microsomal D1 and D2 activities were measured by the release of (125)I from (125)I-reverse triiodothyronine (rT(3)) under different assay conditions. Rats exposed to 4 degrees C (15, 30, 60, and 120 min) showed progressive reduction in...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1989
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.10.469