Botulinum toxin in headache treatment: Finally a promising path?

Botulinum Toxin – a promising new treatment for overactive bladder

Treatment of severe axillary Hyperhidrosis with Botulinum toxin A

Background: Severe axillary hyperhidrosis causes considerable emotional stress to individuals affected with this condition. Existing topical and surgical therapies are either ineffective or associated with unacceptable morbidity and sequelae. Objective: In this study we attempted to determine the effect of botulinum toxin A (Dysport) in the treatment of axillary hyperhidrosis. Patients and Meth...

Effective Botulinum Toxin Injection Guide for Treatment of Temporal Headache

This study involved an extensive analysis of published research on the morphology of the temporalis muscle in order to provide an anatomical guideline on how to distinguish the temporalis muscle and temporalis tendon by observing the surface of the patient's face. Twenty-one hemifaces of cadavers were used in this study. The temporalis muscles were dissected clearly for morphological analysis b...

Botulinum toxin--role in headache prophylaxis.

The mechanism of action of botulinum toxin for its effect in migraine is thought to be through its ability to block nociception at the nerve fiber level and its effects on muscle spindle gamma efferent fibers, resulting in altered sensory feedback. Botulinum toxin may inhibit release of neuropeptides in the peripheral trigeminal vascular system and effect feedback onto the migraine generator to...

Botulinum toxin for treatment of primary chronic headache disorders.

Migraine. Since the 2002 TEC Assessment, 1 new study meeting selection criteria has appeared. Published in 2004 (n=60), this trial randomized patients to saline placebo, low-dose BTX-A, or high-dose BTX-A. No significant differences were reported at 3 months for any of 7 pain-related outcomes. The low dose of BTX-A had a lower rate of accompanying symptoms (photophobia, phonophobia, nausea and ...