Brain networks underlying vulnerability and resilience to drug addiction
نویسندگان
چکیده
منابع مشابه
Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction.
We hypothesize that drug addiction can be viewed as the endpoint of a series of transitions from initial voluntary drug use through the loss of control over this behaviour, such that it becomes habitual and ultimately compulsive. We describe evidence that the switch from controlled to compulsive drug seeking represents a transition at the neural level from prefrontal cortical to striatal contro...
متن کاملNeural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction
We hypothesize that drug addiction can be viewed as the endpoint of a series of transitions from initial voluntary drug use through the loss of control over this behaviour, such that it becomes habitual and ultimately compulsive. We describe evidence that the switch from controlled to compulsive drug seeking represents a transition at the neural level from prefrontal cortical to striatal contro...
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Since the first study in stimulant-dependent individuals using structural MRI was published fifteen years ago, much evidence has accumulated on brain abnormalities associated with stimulant drug dependence. Here we conducted a voxel-based morphometry meta-analysis of published MRI data in stimulant-dependent individuals to clarify the most robust abnormalities underlying the disorder. We found ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2020
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.2002509117