Budding and fission of vesicles
نویسندگان
چکیده
منابع مشابه
Phase-field modeling of the dynamics of multicomponent vesicles: Spinodal decomposition, coarsening, budding, and fission.
We develop a thermodynamically consistent phase-field model to simulate the dynamics of multicomponent vesicles. The model accounts for bending stiffness, spontaneous curvature, excess (surface) energy, and a line tension between the coexisting surface phases. Our approach is similar to that recently used by Wang and Du [J. Math. Biol. 56, 347 (2008)] with a key difference. Here, we concentrate...
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We present a model of bi-phasic vesicles in the limit of large surface tension. In this regime, the vesicle is completely stretched and well described by two spherical caps with a fold, which concentrates the membrane stress. The conservation laws and geometric constraints restrict the space of possible shapes to a pair of solutions labeled by a parameter sigma given by line tension/pressure. F...
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Polarization is a fundamental cellular property, which is essential for the function of numerous cell types. Over the past three to four decades, research using the best-established yeast systems in cell biological research, Saccharomyces cerevisiae (or budding yeast) and Schizosaccharomyces pombe (or fission yeast), has brought to light fundamental principles governing the establishment and ma...
متن کاملBudding dynamics of multicomponent tubular vesicles.
Real-time budding dynamics of multicomponent, tubular lipid vesicles was investigated. By using a fluorescence microscope, three typical growth modes of the buds were observed, corresponding, respectively, to bud growth through coalescence between flat patches, a bud and a patch, as well as that of two buds. The spatial and temporal scales measured in the observation were used to estimate the b...
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Endosomes along the degradation pathway leading to lysosomes accumulate membranes in their lumen and thus exhibit a characteristic multivesicular appearance. These lumenal membranes typically incorporate downregulated EGF receptor destined for degradation, but the mechanisms that control their formation remain poorly characterized. Here, we describe a novel quantitative biochemical assay that r...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1993
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(93)81203-7