C-terminal extension of calmodulin-like 3 protein fromOryza sativaL.: interaction with a high mobility group target protein

بررسی گلیکوزیلاسیون آنتی ژن c-terminal msp1 (c-terminal merozoite surface protein) در پلاسمودیوم فالسیپاروم

مالاریا یکی از بیماری های مهم انگلی در کشورهای گرمسیری دنیا است. پلاسمودیوم فالسیپاروم انگل تک یاخته ای است که تب سه یک بدخیم را ایجاد می کند. آنتی ژن های پلاسمودیوم فالسیپاروم در سطح انگل یا در سطح سلول های آلوده ،کاندیداهای عمده جهت تولید واکسن می باشند، مانند: msp 1 و msp2 . کربوهیدرات های متصل به پروتئین های انگل مالاریا بعنوان اپی توپ های آنتی ژنیک مطرح بوده و بوسیله سیستم ایمنی میزبان تشخ...

Neuroinflammation in Autism Spectrum Disorders: the Role of High Mobility Group Box 1 Protein

The pathogenesis of autism spectrum disorder (ASD) likely involves genetic and environmental factors, impacting the complex neurodevelopmental and behavioral abnormalities of the disorder. Scientific researches emerging within the past two decades suggest that immune dysfunction and inflammation have pathogenic influences through different mechanisms, all leading to both a chronic state of low ...

High mobility group protein HMGI-C: a molecular target in solid tumor formation

The high mobility group protein HMGI-C is a non-histone chromosomal protein characterized by its capacity to bind in the narrow minor groove of AT-rich DNA. It is thought to act as a so-called architectural transcription factor and to modulate the expression of target genes through the formation of stereospecific complexes on the regulatory regions of these targets. Towards defining its functio...

Interaction of a kinesin-like calmodulin-binding protein with a protein kinase.

Kinesin-like calmodulin-binding protein (KCBP) is a novel member of the kinesin superfamily that is involved in cell division and trichome morphogenesis. KCBP is unique among all known kinesins in having a myosin tail homology-4 region in the N-terminal tail and a calmodulin-binding region following the motor domain. Calcium, through calmodulin, has been shown to negatively regulate the interac...

HMGIC (High mobility group protein isoform I-C)