Calreticulin Regulates Transforming Growth Factor-β-stimulated Extracellular Matrix Production
نویسندگان
چکیده
منابع مشابه
Calreticulin (CRT) regulates Transforming Growth Factor-β (TGF-β) stimulated extracellular matrix production
Background: Endoplasmic reticulum (ER) stress is associated with fibrotic diseases although the mechanisms are not completely understood. Results: The ER stress protein calreticulin regulates TGF-β stimulated extracellular matrix through control of intracellular calcium and NFAT signaling. Conclusion: Calreticulin is necessary for TGF-β stimulated extracellular matrix production. Significance: ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2013
ISSN: 0021-9258
DOI: 10.1074/jbc.m112.447243