Can Shaker Potassium Channels be Locked in the Deactivated State?
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چکیده
منابع مشابه
Can Shaker Potassium Channels be Locked in the Deactivated State?
For structural studies it would be useful to constrain the voltage sensor of a voltage-gated channel in its deactivated state. Here we consider one Shaker potassium channel mutant and speculate about others that might allow the channel to remain deactivated at zero membrane potential. Ionic and gating currents of F370C Shaker, expressed in Xenopus oocytes, were recorded in patches with internal...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 2004
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.200409057