Cancer immunotherapy based on blocking immune suppression mediated by an immune modulator LAIR-1
نویسندگان
چکیده
منابع مشابه
Blocking indolamine 2,3 dioxygenase mediated rebound immune suppression improves systemic anti-tumor effects of radio-immunotherapy
Immunotherapy can paradoxically up-regulate immunosuppressive pathways, a phenomenon we term “rebound immunosuppression”. One such pathway is the immunosuppressive enzyme indolamine-2,3-dioxygenase (IDO). Here, we postulated that IDO blockade will improve immunotherapy efficacy by preventing rebound immune-suppression. It has been previously shown that immunotherapy consisting of intralesional ...
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ژورنال
عنوان ژورنال: OncoImmunology
سال: 2020
ISSN: 2162-402X
DOI: 10.1080/2162402x.2020.1740477