Cancer Patterns in Different Racial and Ethnic Groups in Singapore, With Some Reference to Other Asia-Pacific Groups

Racial and Ethnic Groups

Nicotine metabolism in three ethnic/racial groups with different risks of lung cancer.

Previously, we documented that smoking-associated lung cancer risk is greater in Hawaiians and lower in Japanese compared with Whites. Nicotine metabolism by cytochrome P450 2A6 (CYP2A6) varies across ethnicity/race and is hypothesized to affect smoking behavior. We investigated whether higher CYP2A6 activity results in the smoker extracting more nicotine (adjusting for cigarettes per day) and ...

FREQUENCY OF C3435 MDR1 AND A6896G CYP3A5 SINGLE NUCLEOTIDE POLYMORPHISM IN AN IRANIAN POPULATION AND COMPARISON WITH OTHER ETHNIC GROUPS

 ABSTRACT Background: It is well recognized that different patients respond in different ways to medications. The inter-individual variations are greater than the intera- individual variations, a finding consistent with the notion that inheritance is a determinant of drug responses. The recent identification of genetic polymorphisms in drug-metabolizing enzymes and drug transporters led to the ...

Ectopic Fat Depots and Coronary Artery Calcium in South Asians Compared With Other Racial/Ethnic Groups

BACKGROUND South Asians have a low body mass index and high prevalence of cardiovascular disease (CVD) relative to other racial/ethnic groups. Radiographically detected ectopic fat distribution is better associated with CVD than body mass index. We assessed whether differences in ectopic fat depots explained differences in the prevalence/severity of coronary artery calcium (CAC), a predictor of...

Diseases and Different Ethnic Groups

The UK boasts a culturally diverse population with ethnic minorities accounting for 14% of the population in the 2011 census. [1]This represented an increase in the percentage of ethnic members of the population which was around 9% in 2001 and 6% in 1991. Caution is needed when making direct comparisons between censuses as there have been changes in questions and tick boxes which encourage the ...