Candidate Gene Polymorphisms Do Not Differ Between Newborns With Stroke and Normal Controls
نویسندگان
چکیده
منابع مشابه
Candidate gene polymorphisms do not differ between newborns with stroke and normal controls.
BACKGROUND AND PURPOSE Neonatal stroke is increasingly recognized with an estimated incidence of one in 4000 live births per year. Pathways involved in the pathophysiology of neonatal stroke are diverse and may include thrombosis and thrombolysis, vascular reactivity, and inflammation. METHODS We compared frequencies of polymorphisms in genes regulating thrombosis and thrombolysis, nitric oxi...
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BACKGROUND AND PURPOSE Ischemic stroke (IS) is a multifactorial disorder with strong evidence from twin, family, and animal model studies suggesting a genetic influence on risk and prognosis. Several candidate genes for IS have been proposed, but few have been replicated. We investigated the contribution of 67 candidate genes (369 single nucleotide polymorphisms [SNPs]) on the risk of IS in a N...
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CSF abnormalities have been reported in CSF leakage syndrome. However, the mechanism for these CSF changes is actually unknown and they may indicate impaired CSF flow or blood-CSF barrier. Angiopoietin-2 (Ang-2), a protein which is expressed and released by endothelial cells, has been associated with increased vascular permeability. In the assumption that CSF changes are due to an impaired bloo...
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BACKGROUND AND PURPOSE After acute ischemic stroke, the proportion of patients with detectable lesions on fluid-attenuated inversion recovery (FLAIR) MRI sequences increases over time. We investigated whether thrombolysis was less effective in FLAIR-positive versus -negative patients. METHODS In this single-center hospital-based study, all consecutive patients with ischemic stroke who underwe...
متن کاملCognitive correlates of HVOT performance differ between individuals with mild cognitive impairment and normal controls.
OBJECTIVE To clinically characterize performance on the Hooper Visual Organization Test (HVOT) among participants with mild cognitive impairment (MCI) and to identify naming and executive functioning correlates associated with HVOT performance among MCI participants and normal controls (NC). BACKGROUND The HVOT is a common neuropsychological instrument that measures visuospatial skills and ag...
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ژورنال
عنوان ژورنال: Stroke
سال: 2006
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000244810.91105.c9