CANHEART: Is HDL cholesterol a cardiovascular specific risk factor?
نویسندگان
چکیده
منابع مشابه
CANHEART: Is HDL cholesterol a cardiovascular specific risk factor?
Initial observational studies have identified high-density lipoprotein cholesterol (HDL-C) as an independent predictor of cardiovascular (CV) risk, even in patients on optimal statin therapy. However, the notion that higher HDL-C is better, has been seriously challenged by the results from several recent clinical and genetic trials. Data from the CANHEART study serve to clarify the relation bet...
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It has been known for quite a long time that the concentration of HDL-cholesterol correlates inversely with cardiovascular disease (CVD) risk and that low HDL-cholesterol is an independent CVD risk factor. This review aims to highlight evidence on several topics concerning the role of HDL particles and the importance of HDL-cholesterol. The main antiatherogenic functions of HDL particles are pr...
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Dyslipidaemia is one of the major risk factors for the development of cardiovascular disease, which remains the leading cause of death in the world. Despite major advances in the treatment of dyslipidaemia, residual cardiovascular risk remains high in a significant number of patients, a fact that has prompted intensive investigation of medications raising HDL-cholesterol (HDL-C). Indeed, robust...
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High concentrations of HDL cholesterol are considered to indicate efficient reverse cholesterol transport and to protect from atherosclerosis. However, HDL has been suggested to be dysfunctional in ESRD. Hence, our main objective was to investigate the effect of HDL cholesterol on outcomes in maintenance hemodialysis patients with diabetes. Moreover, we investigated the associations between the...
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ژورنال
عنوان ژورنال: Global Cardiology Science and Practice
سال: 2017
ISSN: 2305-7823
DOI: 10.21542/gcsp.2016.34