Carotid endarterectomy (CEA) risk stratification for adverse events at one year follow-up: the role of preoperative functional capacity scores, age, BNP and hemoglobin

The aim of the study was to evaluate combination functional status tools (American Society Anesthesiologists Physical Status Classification System (ASA PS)) status, Metabolic Equivalent Task (METs), Revised Cardiac Risk Index for Pre-Operative (RCRI) largely used in preoperative risk assessment with humoral variables building powerful predictive models Major Adverse Cerebrovascular Events (MACCE) a one-year follow-up after carotid endoarterectomy (CEA). All consecutive patients undergoing CEA during 12-month period, were enrolled this prospective observational study. Demographic data, capacity (FC) measured by stratification scores RCRI, ASA physical METs and levels hemoglobin Brain Natriuretic Peptide (Pro-BNP), coexisting comorbidities, have been collected. 201 under local anesthesia (men 137 (68.16%), women 64 (31.84%)) median age 75 years (Interquartile range (IQR) 67–80 years), Body mass index (BMI) 26.23 (IQR 24.4–28.89) enrolled. Combination all studied leave at good prognostic tool AUC 0.93 (Sensitivity (SEN) 46.6, Specificity (SPEC) 95.7). Preoperative correlate 3 months (p = 0.018), while BNP 12 shows correlation adverse events 0.004). Age has significant between demographic anthropometric factors 0.002). MACCE may adversely affect short- long-term outcomes CEA. Evaluation combined biomarkers such as pro-BNP hemoglobin, improve surgery.