Case-only gene-environment interaction studies: when does association imply mechanistic interaction?
نویسندگان
چکیده
منابع مشابه
A Comparison of Sample Size and Power in Case-Only Association Studies of Gene-Environment Interaction
Assuming continuous, normally distributed environmental and categorical genotype variables, the authors compare 6 case-only designs for tests of association in gene-environment interaction. Novel tests modeling the environmental variable as either the response or the predictor and allowing a genetic variable with multiallelic variants are included. The authors show that tests imposing the same ...
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ژورنال
عنوان ژورنال: Genetic Epidemiology
سال: 2009
ISSN: 0741-0395
DOI: 10.1002/gepi.20484