CCL18-induced LINC00319 promotes proliferation and metastasis in oral squamous cell carcinoma via the miR-199a-5p/FZD4 axis
نویسندگان
چکیده
منابع مشابه
MiR‐375/SLC7A11 axis regulates oral squamous cell carcinoma proliferation and invasion
We aimed to detect the functions of miR-375/SLC7A11 axis on oral squamous cell carcinoma (OSCC) cell proliferation and invasion. Expression levels of miR-375 and SLC7A11 in OSCC tissues and cells were measured with RT-qPCR and western blot. Targeting site was predicted by TargetScan and confirmed by dual luciferase reporting assay. By way of manipulating the expression level of miR-375 and SLC7...
متن کاملCorrelation between p33ING1b Cytoplasmic Transfer and Lymph Node Metastasis in Oral Squamous Cell Carcinoma
Background: Oral squamous cell carcinoma is the sixth most common malignancy in the world today. ING1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. Transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. The objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...
متن کاملTNF-Alpha Promotes Invasion and Metastasis via NF-Kappa B Pathway in Oral Squamous Cell Carcinoma
BACKGROUND Recent evidence reveals that the inflammatory microenvironment is associated with tumor migration, invasion, and metastasis. Tumor necrosis factor-α (TNF-α) play a vital role in regulation of the inflammatory process in tumor development. Nuclear factor-kappa B (NF-κB) is one of the key transcription factors which regulate processes in tumor promotion. The aim of this study was to ex...
متن کاملMetastasis via Peritumoral Lymphatic Dilation in Oral Squamous Cell Carcinoma
PURPOSE Nodal metastasis is the main prognostic factor in the patients with oral squamous cell carcinoma (OSCC). We investigated the association between tumor-associated lymphatics and OSCC characteristics. METHODS Thirty-four specimens were used for the immunohistochemical staining with the antibody for vascular endothelial growth factor (VEGF)-C, VEGF-D, VEGF receptor (VEGFR)-3, phosphoryla...
متن کاملClinicopatholgic Parameters Associated With Regional Lymph Node Metastasis In Oral Squamous Cell Carcinoma: A Retrospective Study
Background and Objective: Oral cancer accounts for less than 3% of all cancers. Despite recent improvement in diagnostic and treatment methods, the overall survival of the disease is unfavorable. Several studies have been performed to assess factors influencing lymph node metastasis and prognosis. The aim of this study was to evaluate some clinical and pathological factors influencing lymph ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2020
ISSN: 2041-4889
DOI: 10.1038/s41419-020-02978-w