CCL25 increases thymopoiesis after androgen withdrawal
                    
                        
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منابع مشابه
IMMUNOBIOLOGY CCL25 increases thymopoiesis after androgen withdrawal
Although studies have demonstrated that androgen withdrawal increases thymic size, molecular mechanisms underlying this expansion remain largely unknown. We show that decreased androgen signaling leads to enhanced immigration of bone marrow T-cell precursors, as manifested by both an early increase of early thymic progenitors (ETP) and improved uptake of adoptively transferred quantified precur...
متن کاملResults of androgen withdrawal monotherapy
Prostate cancer is the most frequent visceral malignancy and the second leading cause of death in American men. It has been estimated that approximately 184 500 new cases will be diagnosed and over 39 200 men will die from prostate cancer in the United States in 1998 (Landis et al. 1998). Despite public awareness of prostate cancer, many apparently localized diseases will be upstaged after path...
متن کاملSkeletal effects of androgen withdrawal.
Hypogonadism is considered to be one of the major risk factors for osteoporosis in men. Therefore, it is an important goal for skeletal research to improve our understanding of the skeletal effects of androgens. Androgen deficiency during growth is associated with a failure to acquire normal peak bone mass, and there is good evidence that the effects of androgens on skeletal growth and the deve...
متن کاملZinc supplementation increases zinc status and thymopoiesis in aged mice.
The age-related decline in lymphocyte development and function coincides with impaired zinc status in the elderly. Thymic involution and reduced immune responsiveness are classic hallmarks of both aging and zinc deficiency, resulting in decreased host defense and an increased susceptibility to infections. Thus, compromised zinc status associated with aging may be an important contributing facto...
متن کاملSpasticity increases during pregabalin withdrawal.
PRIMARY OBJECTIVE To determine whether pregabalin produces long-term spasticity reduction in subjects previously identified as responding in short-term trials. DESIGN, SUBJECTS AND SETTING Prospective service evaluation of patients taking pregabalin for spasticity management for at least 1 year through a tertiary referral rehabilitation clinic. A graduated pregabalin withdrawal was undertaken...
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ژورنال
عنوان ژورنال: Blood
سال: 2008
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2008-04-153627