Cell cycle and 5′-nucleotide phosphodiesterase activities in rat liver
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منابع مشابه
Cyclic 3',5'-Nucleotide Phosphodiesterase Activities in Neurospora crassa
Two molecular species of repressible extracellular phosphodiesterases showing cyclic 2',3'and cyclic 3',5'-nucleotide phosphodiesterase activities were detected in mycelial culture media of wild-type Neurospora crassa and purified. The two molecular species were found to be monomeric and polymeric forms of an enzyme constituted of identical subunits having molecular weights of 50,000. This enzy...
متن کاملRat liver nucleotide pyrophosphatase/phosphodiesterase is an efficient adenylyl transferase.
Rat liver nucleotide pyrophosphatase/phosphodiesterase I (NPP/PDE) catalysed efficiently the transfer of adenylate from ATP to alcohols (methanol, ethanol, propanol, ethylene glycol, glycerol, 2, 2-dichloroethanol and glycerol 2-phosphate), which acted as adenylate acceptors competing with water with different efficiencies. NPP/PDE kinetics in alcohol/water mixtures were accounted for by rate e...
متن کاملCyclic nucleotide phosphodiesterase activities in Neurospora crassa.
Cyclic nucleotide phosphodiesterase activities in soluble Neurospora crassa mycelial extracts were resolved into two peaks, phosphodiesterase I and II, by chromatography on DEAE-cellulose columns. Phosphodiesterase I hydrolysed cyclic AMP and cyclic GMP equally well. Phosphodiesterase II was active on cyclic GMP but scarcely active on cyclic AMP. Phosphodiesterase I was resolved by gel filtrati...
متن کاملA cytogenetic analysis of cyclic nucleotide phosphodiesterase activities in Drosophila.
The genome of Drosophila melanogaster has been surveyed for chromosomal regions which exert a dosage effect on the activities of cAMP phosphodiesterase or cGMP phosphodiesterase. Two regions increase cAMP phosphodiesterase activity when present as duplications. A region of the X chromosome increases cAMP phosphodiesterase activity when duplicated and decreases that activity when deficient. This...
متن کاملISOLATION OF RAT LIVER PLASMA MEMBRANES Use of Nucleotide Pyrophosphatase and Phosphodiesterase I as Marker Enzymes
Nucleotide pyrophosphatase and phosphodiesterase I of rat liver have been found to be localized primarily in cell particulates highly enriched with respect to the most commonly accepted plasma membrane marker, 5'-nucleotidase, and therefore should themselves be assigned a plasma membrane localization. The observation that plasma membranes sediment in isotonic sucrose with both nuclear and micro...
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ژورنال
عنوان ژورنال: Cytometry
سال: 2005
ISSN: 0196-4763,1097-0320
DOI: 10.1002/cyto.990020610