Cell death: A dynamic response concept

A Concept of Death

Any meaningful concept of death can only originate in an intact, living, and functioning central nervous system. This system cannot transgress the limits of its power of conceptualization, and one of these is that it cannot imagine its own termination. Therefore, ideas about death must by necessity be developed in the living state by extrapolation and anticipation of an unknown, frightening, he...

Death, Brain Death, and the Death of Death: Death as a Concept in Continuing Evolution

Resilience as a dynamic concept.

The concept of resilience has as its starting point the recognition that there is huge heterogeneity in people's responses to all manner of environmental adversities. Resilience is an inference based on evidence that some individuals have a better outcome than others who have experienced a comparable level of adversity; moreover, the negative experience may have either a sensitizing effect or a...

Oriented Cell Division as a Response to Cell Death and Cell Competition

The imaginal disc epithelia that give rise to the adult ectoderm of Drosophila can compensate to produce normal adult organs after damage. We looked at the local response to cell death by using two genetic methods to elevate cell death rates. During cell competition, sporadic cell death occurs predictably along the boundaries between populations of competing wild-type and "Minute" cells (M/+). ...

Children's concept of death and sibling death from trauma.

Factors influencing children's concept of death (their understanding of finality, inevitability, and universality) were examined. A bereaved group of 29 siblings (5 to 12 years of age) of children who died from trauma were interviewed 13 to 17 months after their sibling's death. A comparison group (n = 29) of nonbereaved siblings who had not experienced a sibling's death was matched for age, ra...