Cellular and molecular mechanisms of cyclosporin nephrotoxicity.
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چکیده
منابع مشابه
Cellular and molecular mechanisms of cyclosporin nephrotoxicity.
Cyclosporin therapy is associated with several forms of nephrotoxicity, the most significant of which are reversible impairment of glomerular filtration and irreversible interstitial fibrosis. Impaired glomerular filtration is due to both reduction in Kf, the glomerular capillary ultrafiltration coefficient, and to reduction in renal blood flow. The mechanisms responsible for the low Kf are not...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1990
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v12162