Cerebral blood flow measurements with 15O-water PET using a non-invasive machine-learning-derived arterial input function
نویسندگان
چکیده
منابع مشابه
Cerebral blood flow with [15O]water PET studies using an image-derived input function and MR-defined carotid centerlines.
Full quantitative analysis of brain PET data requires knowledge of the arterial input function into the brain. Such data are normally acquired by arterial sampling with corrections for delay and dispersion to account for the distant sampling site. Several attempts have been made to extract an image-derived input function (IDIF) directly from the internal carotid arteries that supply the brain a...
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UNLABELLED Regional myocardial blood flow (MBF) can be measured with 15O-water and PET using the 1-tissue-compartment model with perfusable tissue fraction, which provides an MBF value that is free from the partial-volume effect. Studies with 15O-water have several advantages, such as the ability to repeat a scan. However, because of the short scanning time and the small distribution volume of ...
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Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany To quantify CBF studies using [O]water PET an input function must be provided, e.g. by means of arterial blood sampling. An image derived input function (IDIF) gained from the dynamic PET images may be a non-invasive alternative. The time-activity curve (TAC) of the blood can be obtained from a volume of interest ...
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UNLABELLED (15)O-Water and dynamic PET allow noninvasive quantification of myocardial blood flow (MBF). However, complicated image analyzing procedures are required, which may limit the practicality of this approach. We have designed a new practical algorithm, which allows stable, rapid, and automated quantification of regional MBF (rMBF) using (15)O-water PET. We designed an algorithm for sett...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2021
ISSN: 0271-678X,1559-7016
DOI: 10.1177/0271678x21991393