Cerium Oxide Nanoparticles: Synthesis and Characterization for Biosafe Applications

Due to its excellent physicochemical properties, cerium oxide (CeO2) has attracted much attention in recent years. CeO2 nanomaterials (nanoceria) are widely being used, which resulted them getting released the environment, and exposure humans (mostly via inhalation) is a major concern. In present study, nanoparticles were synthesized by hydroxide-mediated method further characterized Scanning Electron Microscopy (SEM), Field Emission (FESEM), Energy Dispersive X-ray Spectroscopy (EDX), Fourier Transform Infrared (FTIR), Diffraction (XRD). Human lung epithelial (Beas-2B) cells used assess cytotoxicity biocompatibility activity of nanoparticles. 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) Live/Dead assays performed determine Generation reactive oxygen species (ROS) was assessed ROS assay. MTT assay showed no significant induction cell death even at higher concentrations (100 ?g per 100 ?L) upon Beas-2B cells. revealed that did not induce contribute oxidative stress inflammation leading various disease conditions. Thus, could be applications including biosensors, cancer therapy, catalytic converters, sunscreen, drug delivery.