Challenges of fragment screening
نویسندگان
چکیده
منابع مشابه
Challenges of fragment screening
Fragment-based screening for lead generation has seen tremendous growth and success in the last few years. Furthermore, the careful design of fragment libraries has ensured both that the coverage of chemical space is as great as possible and also that the included fragments have desirable physical properties. This particular effort has thus enhanced the advantages of a fragment-based approach. ...
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ژورنال
عنوان ژورنال: Journal of Computer-Aided Molecular Design
سال: 2009
ISSN: 0920-654X,1573-4951
DOI: 10.1007/s10822-009-9293-0