Chapter 6: Structural Variation and Medical Genomics
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چکیده
منابع مشابه
Chapter 6: Structural Variation and Medical Genomics
Differences between individual human genomes, or between human and cancer genomes, range in scale from single nucleotide variants (SNVs) through intermediate and large-scale duplications, deletions, and rearrangements of genomic segments. The latter class, called structural variants (SVs), have received considerable attention in the past several years as they are a previously under appreciated ...
متن کاملEducation Chapter 6 : Structural Variation and Medical Genomics
Differences between individual human genomes, or between human and cancer genomes, range in scale from single nucleotide variants (SNVs) through intermediate and large-scale duplications, deletions, and rearrangements of genomic segments. The latter class, called structural variants (SVs), have received considerable attention in the past several years as they are a previously under appreciated ...
متن کاملStructural Variation and Medical Genomics
The decade since the assembly of the human genome has witnessed dramatic advances in understanding the genetic differences that distinguish individual humans and that are responsible for specific traits. Genomewide association studies (GWAS) in humans have identified common germline, or inherited, DNA variants that are associated with various common human diseases, including diabetes, heart dis...
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Switchgrass was one of the dominant species of the North American tallgrass prairie and savanna ecosystems that once dominated a large portion of the continent. It is currently used for pasture, hay production, soil conservation, and biomass production for conversion to energy. Switchgrass was selected in 1992 as the herbaceous model species to develop dedicated cellulosic bioenergy crops. Bree...
متن کاملNMR and structural genomics.
The role of NMR in structural genomics is outlined, with particular emphasis on using protein domains as targets. Strategies for domain expression, characterization, and labeling are presented.
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2012
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1002821