Characterization of virus inclusion bodies in bluetongue virus-infected cells

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Phosphorylation of bluetongue virus nonstructural protein 2 is essential for formation of viral inclusion bodies.

In bluetongue virus (BTV)-infected cells, large cytoplasmic aggregates are formed, termed viral inclusion bodies (VIBs), which are believed to be the sites of viral replication and morphogenesis. The BTV nonstructural protein NS2 is the major component of VIBs. NS2 undergoes intracellular phosphorylation and possesses a strong single-stranded RNA binding activity. By changing phosphorylated ami...

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Distribution of inclusion bodies in tissues from 100 dogs infected with canine distemper virus.

One hundred dogs that were positive for canine distemper virus antigen and inclusion bodies in the tonsils were examined for the distribution of inclusion bodies in various tissues. Inclusion bodies were found in the lungs (70 dogs), brains (20 dogs), urinary bladders (73 dogs), stomachs (78 dogs), spleens (77 dogs), and lymph nodes (81 dogs) of the dogs. Based on these results, the tonsils may...

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Interferon induction by bluetongue virus and bluetongue virus ribonucleic acid.

EKSTEEN, P. A . L. & HUISMAN S, H. Interferon induction by bluetongue virus and bluetongue virus ribonucleic acid. Onderstep oort]. vet . R es. 39(3), 125-132 (1972). The stimulation of interferon synthesis by bluetongue virus and by bluetongue virus ribonucleic acid was investigated in order to determine if there is a difference in the mechanism of induction. The molecular mass of the interfer...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1993

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-74-3-525