Chemical exposure levels in printing and coating workers with cholangiocarcinoma (third report)
نویسندگان
چکیده
منابع مشابه
Chemical exposure levels in printing and coating workers with cholangiocarcinoma (third report).
OBJECTIVE This study aimed to identify the chemicals used by five printing workers and one coating worker who developed cholangiocarcinoma and estimate the workers' levels of chemical exposure. METHODS We obtained information on chemicals from the Ministry of Health, Labour and Welfare, Japan, and estimated working environment concentrations of the chemicals in printing and coating rooms and ...
متن کاملChemical exposure levels in printing workers with cholangiocarcinoma (second report).
OBJECTIVE In several Japanese printing plants, printing workers have suffered from cholangiocarcinoma. 1,2-dichloropropane (1,2-DCP) is considered to be a causative agent, and whether or not other chemicals also contribute to the development of this disease has not been conclusively determined. This study aimed to identify the chemicals used by seven printing workers who developed cholangiocarc...
متن کاملTwo offset printing workers with cholangiocarcinoma.
OBJECTIVES Previously, the author reported a cluster of 11 cholangiocarcinoma cases exposed to 1,2-dichloropropane (1,2-DCP) and/or dichloromethane (DCM) in an offset proof-printing company. Before that report, the association between the two chemicals and cholangiocarcinoma had not been known. The current study describes two cholangiocarcinoma patients exposed to 1,2-DCP or DCM in different of...
متن کاملHypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes
Cholangiocarcinoma is a relatively rare cancer, but its incidence is increasing worldwide. Although several risk factors have been suggested, the etiology and pathogenesis of the majority of cholangiocarcinomas remain unclear. Recently, a high incidence of early-onset cholangiocarcinoma was reported among the workers of a printing company in Osaka, Japan. These workers underwent high exposure t...
متن کاملCholangiocarcinoma among Workers in the Printing Industry: Using the Nordic Occupational Cancer Database to Elucidate a Cluster Report from Japan
inverse relation to blood lead level (SMRS 11.1, 3.2, 0.9. 0.8 by increasing category). Numbers were small for other causes of interest (stomach cancer n = 23, kidney cancer n = 28, brain cancer n = 31). SMRs for stroke were low (0.59, 0.57, 0.81. 0.87) but showed a borderline significant increasing trend in Poisson regression (p = -0.08). Conclusion We studied a large cohort with documented le...
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ژورنال
عنوان ژورنال: Journal of Occupational Health
سال: 2015
ISSN: 1341-9145,1348-9585
DOI: 10.1539/joh.15-0170-oa