Chemical predictive modeling of ethyl-p-methoxycinnamate and synthesis of natural lotion from kencur (Kaempferia galanga L.) as sunscreen agents

Solar radiation is essential for the evolution of life on earth. radiation, including ultraviolet (UV), reaches earth's surface. The sun emits three types UV radiation: UVA, UVB, and UVC, which have beneficial harmful effects human body. most important benefit synthesis vitamin D in skin. However, UVB also causes direct photochemical damage to DNA. This study aimed investigate ability compound ethyl-p-methoxycinnamate (EPMS) that available kencur as a sunscreen agent through computational chemistry studies using Hartree-Fock (HF) method time-dependent density functional theory (TD-DFT) perform lotion from extract. investigation began with creating molecular model optimized geometry HF continued spectrum analysis TD-DFT. study's results showed EPMS could be used natural shield. In addition, rhizome made oil water phases organoleptic, pH, homogeneity, spreadability test fitted according Indonesian National Standard (SNI) 16-4399-1996. It indicated potentially agent.