Chemosensitivity test using subrenal capsule assays

[Chemosensitivity study using subrenal capsule assay in urinary transitional cell carcinomas].

A subrenal capsule assay (SRCA) was performed on 34 fresh surgical specimens from 31 urinary transitional cell carcinoma (TCC) patients. On day 6, 97.7% of explants were detected macroscopically and tumor cells were present in 45.6% of all explants microscopically. In control groups, there was a negative correlation between the change in explant size (delta TS) and the percentage of the area of...

Comparison of the subrenal capsule assay and succinate dehydrogenase inhibition test as drug sensitivity tests for cancer.

The same chemotherapeutic agents were tested against fresh surgical explants of solid tumors obtained from 50 patients using the in vivo subrenal capsule (SRC) assay and the in vitro succinate dehydrogenase inhibition (SDI) test in comparison. Control growth adequate to meet evaluable assay criteria was obtained in 36 of the 50 tumors tested in the SRC assay (72.0%). In the SDI test, 46 of 50 t...

Chemosensitivity and Chemoresistance Assays in Cancer

Table of

2.03.01 In Vitro Chemoresistance and Chemosensitivity Assays

Chemosensitivity and Chemoresistance Assays in Cancer

Table of