Chitosan Nanocomposites as Wound Healing Materials: Advances in Processing Techniques and Mechanical Properties

This review discusses the increasing potential of chitosan nanocomposites as viable materials capable targeting these debilitating factors. focuses on various techniques used to process and their mechanical properties. Chitosan are regarded highly effective antimicrobials for treatment chronic wounds. nanocomposites, such chitosan/polyethylene oxide/silica/ciprofloxacin, demonstrate efficient antibacterial activity exhibit no cytotoxicity against Human Foreskin Fibroblast Cell Lines (HFF2). Other studies have also showcased capacity accelerate improve tissue regeneration through increment in number fibroblast cells angiogenesis reduction inflammation phase. The layer-by-layer technique has benefits, ensuring its suitability preparing drug delivery wound dressing applications. While co-precipitation route requires a cross-linker achieve stability during processing, solution-casting can produce stable without cross-linker. By using solution casting method, fillers multi-walled carbon nanotubes (MWCNTs) halloysite (HTs) be uniformly distributed chitosan, leading improved effects achieved with introduction AgNPs or ZnO. With understanding biological mechanisms that control diseases, there is an influx novel into mainstream care market.