Chromosomal damage and ageing: effect on micronuclei frequency in peripheral blood lymphocytes
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چکیده
منابع مشابه
Chromosomal damage and ageing: effect on micronuclei frequency in peripheral blood lymphocytes.
BACKGROUND Instability in the organization and expression of the genetic material has been hypothesized as the basic mechanism of ageing. OBJECTIVE To quantify the effect of ageing on chromosomal damage as measured by spontaneous micronuclei (MN) frequency in peripheral blood lymphocytes. METHOD Analysis of a large population sample from two laboratories applying the cytokinesis-block techn...
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ژورنال
عنوان ژورنال: Age and Ageing
سال: 1999
ISSN: 1468-2834
DOI: 10.1093/ageing/28.4.393