Chromosome architecture is a key element of bacterial cellular organization
نویسندگان
چکیده
منابع مشابه
Spatial organization of a replicating bacterial chromosome.
Emerging evidence indicates that the global organization of the bacterial chromosome is defined by its physical map. This architectural understanding has been gained mainly by observing the localization and dynamics of specific chromosomal loci. However, the spatial and temporal organization of the entire mass of newly synthesized DNA remains elusive. To visualize replicated DNA within living c...
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Bacterial chromosomes are generally approximately 1000 times longer than the cells in which they reside, and concurrent replication, segregation, and transcription/translation of this crowded mass of DNA poses a challenging organizational problem. Recent advances in cell-imaging technology with subdiffraction resolution have revealed that the bacterial nucleoid is reliably oriented and highly o...
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How the same DNA sequences can function in the three-dimensional architecture of interphase nucleus, fold in the very compact structure of metaphase chromosomes, and go precisely back to the original interphase architecture in the following cell cycle remains an unresolved question to this day. The solution to this question presented here rests on the correlations that were found to hold betwee...
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Garmendia, E. 2017. A Unified Multitude. Experimental Studies of Bacterial Chromosome Organization. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1392. 66 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0140-2. Bacteria are many, old and varied; different bacterial species have been evolving for millions of years and show many disparate life-...
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UNLABELLED Repeated extragenic palindromes (REPs) in the enterobacterial genomes are usually composed of individual palindromic units separated by linker sequences. A total of 355 annotated REPs are distributed along the Escherichia coli genome. RNA sequence (RNAseq) analysis showed that almost 80% of the REPs in E. coli are transcribed. The DNA sequence of REP325 showed that it is a cluster of...
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ژورنال
عنوان ژورنال: Cellular Microbiology
سال: 2012
ISSN: 1462-5814
DOI: 10.1111/cmi.12049